About half of people with migraine who take ibuprofen (Advil®, Motrin®, etc.) will get relief, according to a systematic review of nine studies with a combined total of 4,373 participants. In the studies, just over one-fourth of those who took 400 mgs., and 20% of those who took a 200-mg. dose, were pain-free in two hours compared to 11% of people who took a placebo. Another 57% of those who took the higher dose had their pain reduced to “no worse than mild.” Nausea and other migraine-related symptoms also decreased. Continue Reading
Ibuprofen is an analgesic. It is classified as a nonsteroidal anti-inflammatory drug, commonly referred to as NSAIDS. Other NSAIDS are also used as analgesics. Ibuprofen can be used as a pain reliever or analgesic. It can also be used as a treatment for arthritis, fever or other conditions where inflammation plays a role in creating the symptoms. Unlike steroids, the side effects with ibuprofen are not as likely to be common or severe. The most common side effects include stomach upset, dizziness and tiredness. It may make stomach ulcers worse or cause upper gastrointestinal bleeding. It can have effects on kidney and liver functioning when used chronically. The frequent use of NSAIDs can increase the risk of cardiovascular disease.
Studies with this agent have demonstrated it to be effective in tension-type headache. Other NSAIDS have been shown to be effective in migraine both for prevention of migraine as well as treating the acute migraine attack. Ibuprofen is available over the counter at a reduced dose from the prescription form of t
he medication. A variety of trade names are used including Advil®, Motrin® and Nuprin®.
Diflunisal (the generic name for Dolobid®) is a nonsteroidal anti-inflammatory analgesic. It is a prostaglandin inhibitor and similar to Alleve® and Motrin®. It works for moderate to severe pain and is not habit forming. As with other medications in this class, it may make stomach ulcers worse or cause upper gastrointestinal bleeding. It can have effects on kidney and liver functioning when used chronically.