One of the most frequently encountered triggers of migraine is changes in estrogen levels. As women progress through their child-bearing years, migraines often are more frequent. As menses cease in menopause, the majority of women experience fewer migraine attacks. However, it should be noted that hormonal replacement therapy sometimes causes women to continue with their migraines.
Provera is a progesterone agent often used in hormonal replacement therapy. At one time it was used for prevention of migraine with mixed and unreliable results.