Illness, Chronic Fatigue Syndrome and Migraine

Individuals who suffer from Gulf War illness (GWI) and chronic fatigue syndrome (CFS) often share many of the same symptoms, including migraine.

Researchers from George Washington University in Washington, D.C. recently suggested that the disorders may share a central nervous system dysfunction that could account for the chronic pain, fatigue, and cognitive dysfunction (sometimes described as brain fog) that Gulf War illness, chronic fatigue, and migraine sufferers have in common. Continue Reading

Migraine Treatment Benefits the Whole Patient

Treating migraine brings multiple benefits to migraineurs, including improvement of psychological and social problems that frequently accompany the disorder, new research indicates.

In a review of studies published between 2000 and 2010, researchers found that among migraineurs with and without aura, the most common psychosocial difficulties (PSDs) included: fatigue; emotional problems, especially depression and anxiety; difficulties at work, such as decreased efficiency and absences; problematic social functioning and global disability, which encompasses all the psychosocial problems a person experiences because of migraine.  Continue Reading

New Frontier in Headache Treatment?

Many pharmaceutical companies are researching completely new compounds to attack headaches from different angles. Merck & Co., Inc., announced that a Phase III clinical trial showed that a new compound called telcagepant (formerly known as MK-0974) significantly improved relief of migraine pain and associated symptoms comparable to the triptan zolmitriptan, but with fewer side effects. Continue Reading

Reader’s Mail: Other Ideas for Treating Migraine

Q. I have had migraines for over 20 years. For many years now I have been on a beta-blocker for preventive therapy as I failed to tolerate Imitrex® or Topamax®. My headaches usually begin after excessive stress and fatigue, but can occur anytime. In spite of having a very healthy lifestyle, I still have migraines at least twice a month, which unfailingly last three days. Do you have any other ideas for me? Continue Reading


Studies have shown that verapamil may be effective in the preventive treatment of migraine and cluster headache patients.

Verapamil is a calcium blocker that may work by preventing the constriction of the blood vessels prior to the migraine attack. However, recent genetic studies have suggested that calcium channels in nerve cells may not function normally in migraine. Verapamil is commonly used for blood pressure and heart conditions. It takes at least four to six weeks for it to become effective in treating migraine. Side effects such as ankle swelling, constipation, and fatigue are common.