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Oral contraceptives contain hormones – often a combination of estrogen and progesterone – that prevent ovulation. At one point during the cycle, the estrogen levels in the pill are reduced to allow a normal period to occur. However, the drop in estrogen levels may cause a migraine. Experts have noted that these kinds of headaches are most likely to occur in women who have just started taking oral contraceptives and who have a family history of migraine.1 Sometimes oral contraceptives are actually used to treat migraine,1 but if you find they cause or exacerbate your migraines, you should talk to your healthcare provider. He or she may encourage you to switch to another oral contraceptive (containing lower amounts of hormones) or try other methods of contraception. If this is not possible, your healthcare provider may prescribe a non-steroidal anti-inflammatory agent (NSAID) to be used during the 7-day period when your pills do not contain estrogen to relieve migraine.1
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