Methergine, the brand name for methylergonovine maleate, was originally developed for the treatment of postpartum bleeding and for improvement in the uterine tone. It is related to the ergot amine medications. In addition to its effects on the uterus, Methergine also causes constriction of the smooth muscles in the blood vessels.

This vasoconstriction action makes Methergine useful in several situations as related to some headache patients. It can be helpful in treating vascular headaches, such as migraine (including menstrual migraine) or cluster.

It is more commonly used for prevention of headaches, but can be taken for acute attacks. Because of the vasoconstricting effects, Methergine is used for limited periods of time in most patients and only under careful supervision of a physician.

The side effects of Methergine are similar to those seen with other ergot agent medications. It may cause high blood pressure in some patients.

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Just a note of thanks to the NHF for hosting these helpful online seminars.  The recent "Fibromyalgia and Migraine" was the second Webinar I've attended, and I learned a great deal.

The Webinars are easy to log into, the presentations are professional, and the presenters do not "talk down" to their auditors. The NHF is apparently choosing subject matter experts with care, and the information is up-to-date. 

Again, thank you for the hard work. I look forward to future Webinars.

Deborah S.



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