Enkephalins/Endorphins

These two groups of compounds comprise the basis for the body's own pain fighting mechanisms. The enkephalins are found in many areas of the body, and the endorphins are primarily located within the brain itself. Changes in these compounds and their metabolism have been associated with different headache disorders. Their exact role has not been determined. These compounds could play a role in the cause of headache itself. Some headache therapies may act by working on these chemicals.

Give the gift of
pain relief

Your donation goes to work immediately, helping the NHF in our continuing effort to educate and fund valuable headache research.

Donate Now

Stay Connected

Testimonial

“I do greatly enjoy the NHF Newsletter. It has been a blessing to me to realize I’m not alone and that others are working hard to help those of us who suffer.”

Michael H.

Headwise

NHF Facebook