CGRP: What You Need to Know

By Dr. James Banks, National Headache Foundation Board Member

What is CGRP?

First, some background: CGRP is the abbreviation for Calcitonin Gene-Related Peptide, a protein in the brain and nervous system involved in the transmission of pain and the resultant reaction of tissues and blood vessels. The new medications you are hearing about are actually monoclonal antibodies to either the CGRP itself or the receptors where CGRP lands. 

There are various forms of CGRP in different parts of the body. They all have very different actions. These new drugs are very specific for the nerves and blood vessels involved in migraine. Continue Reading

Individuals with Migraine Presenting in Emergency Department Often Return

A study looking to determine the frequency of emergency department revisits in New York City found that many patients with migraine frequently return within a 6-month period. The results were published in the November edition of Headache.

Migraine leads to more than 1.2 million visits to emergency departments in the United States annually. The authors analyzed 18 emergency departments in New York City in search of the frequency of revisits, as well as sociodemographic factors. Continue Reading

Do You Want Much Better Treatments for Chronic Pain? (For Example, Better Than Opioids?)

Right now, you have a unique opportunity to influence Congress about the need to increase NIH research on understanding chronic pain and opioids that could lead to new treatments. In 2016,  The Alliance for Headache Disorders Advocacy (AHDA), helped to have provisions focused on increasing NIH pain research included in the Comprehensive Addiction and Recovery Act (CARA). CARA was signed into law in July 2016. Since then, the AHDA has been collaborating on a bill to fully fund these provisions. That bill was recently introduced: 

The Opioids and STOP Pain Initiatives Act (H.R.4733 / S.2260)

You can help pass this bill by urging your Members of Congress to co-sponsor it now

Please click on the link below to send emails to your Members of Congress. 

  • Space is provided where you can add a concise description (3 sentences, tops) of why this issue and this research is so important to you. 
  • Please do not make any edits (additions or deletions) to the remainder of the letter. The remainder of the letter is the explanation of the need for the bill and it is vital that this information reach congressional offices intact. 

Please share this with your friends, family, co-workers, or anyone you know who is struggling with chronic pain or opioids. Ask them to take action, too. The voices of the pain and headache disorders community need to ring loudly in D.C.  and you really can make a difference. 

Take Action


Oxygen Therapy Underutilized for Cluster Headache—What Can You Do?

Despite treatment guidelines recommending the use of oxygen for the acute therapy of cluster headache, oxygen remains underutilized. A recent study looking at the cost of oxygen for cluster headache found the reason for its lack of use may be because of poor physician awareness of the treatment, as well as the lack of understanding for how to write and fill a prescription for high-flow oxygen. Continue Reading